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Focal high-grade dysplasia is present.
Need to know the extension of the lesion.
Any involvement of the submucosa and beyond?
If it is confied within the muscularis mucosae, it is at most an adenocarcinoma in-situ. TNM stage: Tis, and the patient is cured.
If it invades to the submucosa and beyond, many times perineural invasion can be found. The clinical outcome is very bad.
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